Innenrücktitelbild: Mechanochemistry‐Amended Barbier Reaction as an Expedient Alternative to Grignard Synthesis (Angew. Chem. 39/2023)
نویسندگان
چکیده
Mechanochemistry makes the next move in advancing organometallic synthesis. In their Research Article (e202305775), Riina Aav, Dzmitry G. Kananovich et al. report a mechanochemical adaptation of Mg-mediated Barbier reaction, which overcomes limitations classic solvent-based approach. Mechanochemical activation enables rapid generation Grignard reagents situ, making process resistant to air and allowing solid Brønsted acids be used as additives improve yields.
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ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2023
ISSN: ['1521-3773', '1433-7851', '0570-0833']
DOI: https://doi.org/10.1002/ange.202310353